SNP array: Difference between revisions

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Revision as of 21:43, 18 January 2022

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{{See also|DNA microarray|SNP genotyping}}

{{expert needed|Computational Biology|date=April 2016}}

In [[molecular biology]], '''SNP array''' is a type of [[DNA microarray]] which is used to detect [[Polymorphism (biology)|polymorphisms]] within a population. A [[single nucleotide polymorphism]] (SNP), a variation at a single site in [[DNA]], is the most frequent type of variation in the genome. Around 335 million SNPs have been identified in the [[human genome]],<ref>{{cite web|title=dbSNP Summary|url=https://www.ncbi.nlm.nih.gov/projects/SNP/snp_summary.cgi|website=www.ncbi.nlm.nih.gov|accessdate=4 October 2017}}</ref> 15 million of which are present at frequencies of 1% or higher across different populations worldwide.<ref name="DurbinAltshuler2010">{{cite journal|author=The 1000 Genomes Project Consortium|title=A map of human genome variation from population-scale sequencing|journal=Nature|volume=467|issue=7319|year=2010|pages=1061–1073|issn=0028-0836|doi=10.1038/nature09534|pmid=20981092|pmc=3042601|bibcode=2010Natur.467.1061T}}</ref>