Revision as of 16:25, 8 May 2021 edit AnomieBOT (talk \| contribs) Bots 6,861,861 edits m Dating maintenance tags: {{Cn}} ← Previous edit		Revision as of 03:04, 18 May 2022 edit undo Smasongarrison (talk \| contribs) Administrators 814,298 edits →Function: rewriting problematic phrases for medical/health related content per WP:MEDLANG on careful language, replaced: suffering from Lupus → with Lupus!WP:SUFFER, those suffer from → those with!WP:SUFFER Tag: AWB Next edit →
Line 93: ==Function== [[File:Complement pathway.svg\|thumb\|270px\|left\|The classical and alternative complement pathways. C1q is the orange part of the [[C1 complex]] at the top of the image.]] It is assumed that the globular ends are the sites for multivalent attachment to the complement fixing sites in immune complexed immunoglobulin. Patients ~~suffering from~~with Lupus erythematosus often have deficient expression of C1q. Genetic deficiency of C1q is extremely rare (approximately 75 known cases) although the majority (>90%) of those ~~suffer from~~have [[Systemic lupus erythematosus\|SLE]]. {{cncitation needed\|date=May 2021}} C1q associates with C1r and C1s in order to yield the [[C1 complex]] (''C1qr<sup>2</sup>s<sup>2</sup>''), the first component of the serum [[complement system]]. Deficiency of C1q has been associated with [[lupus erythematosus]] and [[glomerulonephritis]].<ref name="entrez ciqa"/>

Complement component 1q: Difference between revisions