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The journal publishes both original research and review articles. All articles are open access and licensed under the [[Creative Commons Attribution License]].<ref>{{Cite web |url=http://journals.plos.org/ploscompbiol/s/journal-information |title=PLOS Computational Biology: A Peer-Reviewed Open-Access Journal |website=journals.plos.org |access-date=2017-03-24}}</ref> In 2012, it launched the "Topic Page" review format, which dual-publishes peer-reviewed articles both in the journal and on Wikipedia.<ref>{{Cite journal |last1=Wodak |first1=Shoshana J. |last2=Mietchen |first2=Daniel |last3=Collings |first3=Andrew M. |last4=Russell |first4=Robert B. |last5=Bourne |first5=Philip E. |date=2012-03-29 |title=Topic Pages: PLOS Computational Biology Meets Wikipedia |journal=PLOS Computational Biology |volume=8 |issue=3 |pages=e1002446 |doi=10.1371/journal.pcbi.1002446 |pmc=3315447 |pmid=22479174|bibcode=2012PLSCB...8E2446W }}</ref><ref>{{Cite web |url=http://collections.plos.org/topic-pages |title=PLOS Collections: Topic Pages |website=PLOS Computational Biology |access-date=2017-03-24}}</ref> It was the first publication of its kind to publish in this way.<ref>{{Cite web |url=https://blog.wikimedia.org/2016/10/29/wikipedia-medical-content/ |title=Wikipedia's medical content: A new era of collaboration |website=blog.wikimedia.org |date=29 October 2016 |publisher=[[Wikimedia Foundation]] |access-date=2017-03-24}}</ref>
 
The journal publishes articles for the famous Ten Simple Rules series.<ref>[{{cite web | url=https://collections.plos.org/collection/ten-simple-rules/] | title=Ten Simple Rules }}</ref>
 
==See also==