Mycobacterium avium complex: Difference between revisions

Revision as of 22:39, 13 December 2022

Revision as of 22:26, 16 December 2022

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| binomial2 = ''Mycobacterium avium''

| binomial2_authority = Chester 1901 emend. Thorel et al. 1990

}}

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'''Colony characteristics'''

* Usually, colonies are smooth, rarely rough, and not pigmented [[Colony (biology)|colonies]]. Older colonies may become yellow.

'''Physiology'''

* Growth on [[Löwenstein-Jensen]] medium and [[Middlebrook 7H10 Agar|Middlebrook 7H10 agar]] occurs at 37°C after seven or more days.

* The complex can be (but is not often) resistant to [[isoniazid]], [[ethambutol]], [[rifampin]], and [[streptomycin]].<ref name="pmid29054853">{{cite journal | vauthors = Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA | title = British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD) | journal = Thorax | volume = 72 | issue = Suppl 2 | pages = ii1–ii64 | date = November 2017 | pmid = 29054853 | doi = 10.1136/thoraxjnl-2017-210927 | doi-access = free }}</ref>

'''Differential characteristics'''

* ''M. intracellulare'' and ''M. avium'' form the ''M. avium'' complex (MAC).

* Remarkable [[Internal transcribed spacer|ITS]] heterogeneity is seen within different ''M. intracellulare'' isolates.

== Species ==

* ''[[Mycobacterium avium avium|Mycobacterium avium]]''

** ''[[Mycobacterium avium subsp. paratuberculosis]]''

==Type strains==

* ''M. intracellulare'' type strains include [[American Type Culture Collection|ATCC]] 13950, CCUG 28005, CIP 104243, DSM 43223, JCM 6384, and NCTC 13025.<ref>[http://bacdive.dsmz.de/index.php?search=8403&submit=Search Type strain of ''Mycobacterium intracellulare'' at Bac''Dive'' - the Bacterial Diversity Metadatabase]</ref>

* ''M. avium'' type strains include ATCC 25291, DSM 44156, and TMC 724.<ref>[http://bacdive.dsmz.de/index.php?site=search&rd=8419 Type strain of ''Mycobacterium avium'' at Bac''Dive'' - the Bacterial Diversity Metadatabase]</ref>

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==External links==

* {{MeshName|Mycobacterium avium Complex}}

{{Gram-positive actinobacteria diseases}}