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==Incidence==
[[Brain tumor|Brain tumors]] are the second most common malignancy among children 0-19 years of age, and of those, medulloblastoma is the second most common CNS malignancy.<ref name="seer">James G. Gurney, Malcolm A. Smith, Greta R. Bunin, [http://seer.cancer.gov/publications/childhood/cns.pdf CNS and Miscellaneous Intracranial and Intraspinal Neoplasms], SEER Pediatric Monograph, National Cancer Institute</ref> Medulloblastoma comprises less than 2% of CNS malignancies diagnosed in adults.<ref>[http://cbtrus.org/2005-2006/tables/2006.table12.pdf, Selected Primary Brain and Central Nervous System Tumor Age-Specific Incidence Rates], Central Brain Tumor Registry of the United States, 1998-2002.</ref>
Medulloblastoma has a bimodal incidence at the ages of 4-8 years, then in the early 20s and accounts for ~20% of childhood brain tumors. Males out of female 3:2 or 3:1 in many cases. It is a rapidly growing embryonic tumor that arises in the posterior [[cerebellar vermis]] and neuroepithelial roof of the [[fourth ventricle]]. ▼
▲Medulloblastoma has a bimodal incidence at the ages of 4-8 years, then in the early 20s and accounts for ~20% of childhood brain tumors. Males out of female 3:2 or 3:1 in many cases.
==Pathogenesis==
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