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Importing Wikidata short description: Protein-coding gene in the species Homo sapiens (shortdescs-in-category) |
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{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
The ''' microprocessor complex subunit DGCR8''' ''([[DiGeorge syndrome]] critical region 8)'' is a [[protein]] that in humans is encoded by the {{gene|DGCR8}} [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: DGCR8 DiGeorge syndrome critical region gene 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54487| accessdate = }}</ref> In other animals, particularly the common [[model organism]]s ''[[Drosophila melanogaster]]'' and ''[[Caenorhabditis elegans]]'', the protein is known as ''Pasha'' (partner of [[Drosha]]).<ref>{{cite journal | vauthors = Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ | title = Processing of primary microRNAs by the Microprocessor complex | journal = Nature | volume = 432 | issue = 7014 | pages = 231–5 | date = Nov 2004 | pmid = 15531879 | doi = 10.1038/nature03049 | bibcode = 2004Natur.432..231D | s2cid = 4425505 }}</ref> It is a required component of the [[RNA interference]] pathway.
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