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=== H3K27 Mechanism ===
Polycomb repressive complexes (PRC) [[PRC1|1]] and 2 are recruited to bind to the [[H3K27me3]] gene, which is found at the beginning of ''Drosophila'' embryogenesis. [[PRC2]] then catalyzes the gene’s [[DNA methylation|methylation]], inducing PCR2 recruitment and compacting the chromatin. The research found that PRC2 recruitment is dependent on the presence of the H2AKub sequence. However, even after mutations in the H3K27 residue, PcGs were able to be recruited and revert to their original [[Phenotype|phenotypes]] indicating a transcriptional change in the H3K27 residue<ref>{{Cite journal |last=Marasca |first=Federica |last2=Bodega |first2=Beatrice |last3=Orlando |first3=Valerio |date=2018-04 |title=How Polycomb-Mediated Cell Memory Deals With a Changing Environment: Variations in PcG complexes and proteins assortment convey plasticity to epigenetic regulation as a response to environment |url=https://onlinelibrary.wiley.com/doi/10.1002/bies.201700137 |journal=BioEssays |language=en |volume=40 |issue=4 |pages=1700137 |doi=10.1002/bies.201700137}}</ref>.
== Application of Cellular Memory Modules ==
==References==
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