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Line 31: == Clinical Significance == Photosensitive patients with C2 type I deficiency have poor prognosis. C2 type I deficiency is caused by a 28-base pair gene deletion, resulting in premature termination codon and lack of C2 protein. Patients with LE associated with complement C4 or C2 deficiencies have a better prognosis than those without inherited deficiencies. Complement component 2 deficiency increases risk of autoimmune disorders which may be managed by receiving the adequate care. Clinically, this is significant since Complement component 2 deficiency increases the risk of recurrent bacterial infections, which may be life-threatening. == Other Names == There are numerous forms of naming this gene. For example: ARMD14 C3/C5 convertase CO2 complement component 2 complement component C2 == References ==

Complement component 2: Difference between revisions