Reproducibility: Difference between revisions

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{{Short description|Aspect of scientific research}}
{{About|the reproducibility of scientific research results|reproductive capacity of organisms|fertility|and|fecundity|reproducibility in the context of computer software|Reproducible builds}}
 
'''Reproducibility''', closely related to '''replicability''' and '''repeatability''', is a major principle underpinning the [[scientific method]]. For the findings of a study to be reproducible means that results obtained by an [[experiment]] or an [[observational study]] or in a [[statistical analysis]] of a [[data set]] should be achieved again with a high degree of reliability when the study is replicated. There are different kinds of replication<ref>{{Cite journal|last1=Tsang|first1=Eric W. K.|last2=Kwan|first2=Kai-man|date=1999|title=Replication and Theory Development in Organizational Science: A Critical Realist Perspective|url=http://dx.doi.org/10.5465/amr.1999.2553252|journal=Academy of Management Review|volume=24|issue=4|pages=759–780|doi=10.5465/amr.1999.2553252|issn=0363-7425}}</ref> but typically replication studies involve different researchers using the same methodology. Only after one or several such successful replications should a result be recognized as scientific knowledge.
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Reproducible research is key to new discoveries in [[pharmacology]]. A Phase I discovery will be followed by Phase II reproductions as a drug develops towards commercial production. In recent decades Phase II success has fallen from 28% to 18%. A 2011 study found that 65% of medical studies were inconsistent when re-tested, and only 6% were completely reproducible.<ref>{{Cite journal|last1=Prinz |first1=F. |last2=Schlange |first2=T. |last3=Asadullah |first3=K. |doi=10.1038/nrd3439-c1 |title=Believe it or not: How much can we rely on published data on potential drug targets? |journal=Nature Reviews Drug Discovery |volume=10 |issue=9 |page=712 |year=2011 |pmid=21892149 |doi-access=free}}</ref>
 
==Reproducibility of software==
{{Main|Reproducible builds}}
 
==Noteworthy irreproducible results==