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'''Transcripts of unknown function (TUFs)''' is the name that has been suggested for known [[RNA|RNA transcripts]] of [[DNA]] whose function is unclear. Most TUFs are probably [[Non-coding RNA|ncRNAs]], such as [[RNAi]] or [[snoRNA]]s, but could also represent a whole new class of ncRNA.<ref name="Gingeras">{{cite journal | last = Gingeras | first = Thomas R. | year = 2007 | title = Origin of phenotypes: Genes and transcripts | journal = Genome Research | volume = 17| issue = 6 | pages = 682–690 | doi = 10.1101/gr.6525007 | pmid = 17567989 | doi-access = free }}</ref> The [[DNA sequence]]s for TUFs reside in the [[Intergenic region|intergenic]] or [[intron]]ic regions of the [[genome]], which is often called [[junk DNA]].
== Categories
Broadly speaking, TUFs can be classified into three categories:<ref name="Gingeras" />
# TUFs that are complementary to [[Sense (molecular biology)|sense transcripts]] of protein-coding [[gene]]s
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