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Complications are less frequent in comparison to a [[cervical conization|cold-knife conization]] but can include [[infection]] and [[hemorrhage]].<ref>{{Cite journal |last1=Jiang |first1=Yanming |last2=Chen |first2=Changxian |last3=Li |first3=Li |date=2017-01-26 |title=Comparison of Cold-Knife Conization versus Loop Electrosurgical Excision for Cervical Adenocarcinoma In Situ (ACIS): A Systematic Review and Meta-Analysis |journal=PLOS ONE |volume=12 |issue=1 |pages=e0170587 |doi=10.1371/journal.pone.0170587 |issn=1932-6203 |pmc=5268480 |pmid=28125627 |bibcode=2017PLoSO..1270587J |doi-access=free }}</ref>
A survey study hasdid indicatednot thatfind thesignificant LEEPeffects procedure does not appear to affecton [[fertility]].<ref>{{cite journal |vauthors=Turlington WT, Wright BD, Powell JL |title=Impact of the loop electrosurgical excision procedure on future fertility |journal=J Reprod Med |volume=41 |issue=11 |pages=815–8 |date=November 1996 |pmid=8951130 }}</ref> On the other handHowever, a [[case-control study]] has found an association between surgical treatment of CIN lesions and risk of [[female infertility|infertility]] or subfertility, with an odds ratio of approximately 2.<ref>{{Cite journal | last1 = Spracklen | first1 = C. N. | last2 = Harland | first2 = K. K. | last3 = Stegmann | first3 = B. J. | last4 = Saftlas | first4 = A. F. | title = Cervical surgery for cervical intraepithelial neoplasia and prolonged time to conception of a live birth: A case-control study | doi = 10.1111/1471-0528.12209 | journal = BJOG: An International Journal of Obstetrics & Gynaecology | volume = 120 | issue = 8 | pages = 960–965 | year = 2013 | pmid = 23489374 | pmc =3691952 }}</ref> Scarring of the cervix is a theoretical mechanism of causing trouble conceiving. This scar tissue can be massaged or broken up in a number of ways, thus allowing the cervical opening to dilate back to normal size.
A [[cohort study]] came to the resultconcluded that women with a time interval from LEEP to pregnancy of less than 12 months, compared with 12 months or more, were at significantly increased risk for [[miscarriage]], with risk of miscarriage of 18% compared with 4.6%, respectively, suggesting that increasing latency times from treatment to pregnancy initiation improves outcomes.<ref name=Chescheir2013>{{Cite journal | last1 = Conner | first1 = S. N. | last2 = Cahill | first2 = A. G. | last3 = Tuuli | first3 = M. G. | last4 = Stamilio | first4 = D. M. | last5 = Odibo | first5 = A. O. | last6 = Roehl | first6 = K. A. | last7 = MacOnes | first7 = G. A. | doi = 10.1097/01.AOG.0000435454.31850.79 | title = Interval from Loop Electrosurgical Excision Procedure to Pregnancy and Pregnancy Outcomes | journal = Obstetrics & Gynecology | volume = 122 | issue = 6 | pages = 1154–9 | year = 2013 | pmid = 24201682| pmc = 3908542}}</ref> OnA thelarge other[[meta-analysis]] hand,concluded nothat increasedwomen riskwith wasCIN identifiedhave a higher baseline risk for [[preterm birth]] afterthan the general population and that LEEP as the treatment for CIN could increase this risk further. The risk of preterm birth appears to increase with multiple treatments and increasing amounts of tissue removed.<ref name=Chescheir2013"pmid29095502">{{cite journal | vauthors = Kyrgiou M, Athanasiou A, Kalliala IE, Paraskevaidi M, Mitra A, Martin-Hirsch PP, Arbyn M, Bennett P, Paraskevaidis E | title = Obstetric outcomes after conservative treatment for cervical intraepithelial lesions and early invasive disease | journal = The Cochrane Database of Systematic Reviews | volume = 11 | issue = 11 | pages = CD012847 | date = November 2017 | pmid = 29095502 | pmc = 6486192 | doi = 10.1002/14651858.CD012847 }}</ref>
However a large [[meta-analysis]] concluded that women with CIN have a higher baseline risk for preterm birth than the general population and that LEEP as the treatment for CIN probably increase this risk further. Also, the risk of preterm birth appears to increase with multiple treatments and increasing amounts of tissue removed.<ref name="pmid29095502">{{cite journal | vauthors = Kyrgiou M, Athanasiou A, Kalliala IE, Paraskevaidi M, Mitra A, Martin-Hirsch PP, Arbyn M, Bennett P, Paraskevaidis E | title = Obstetric outcomes after conservative treatment for cervical intraepithelial lesions and early invasive disease | journal = The Cochrane Database of Systematic Reviews | volume = 11 | issue = 11 | pages = CD012847 | date = November 2017 | pmid = 29095502 | pmc = 6486192 | doi = 10.1002/14651858.CD012847 }}</ref>
A study found that women reported a statistically significant decrease in sexual satisfaction following LEEP.<ref name=":0">{{cite journal|title=Sexual function after loop electrosurgical excision procedure for cervical dysplasia|first1=Namfon|last1=Inna|first2=Yupin|last2=Phianmongkhol|first3=Kittipat|last3=Charoenkwan|date=1 March 2010|journal=J Sex Med|volume=7|issue=3|pages=1291–1297|doi=10.1111/j.1743-6109.2009.01633.x|pmid=19968775}}</ref>
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