DNA computing: Difference between revisions

Revision as of 12:34, 18 July 2023

Revision as of 07:50, 3 December 2023

Line 48:

|bibcode= 2019ITNan..18..252E|s2cid= 5616325}}

</ref>

While both the designs face some issues (such as reaction leaks), this appears to represent a significant breakthrough in the field of DNA computing. Some other groups have also attempted to address the gate reusability problem.<ref>{{Cite journal|last1=Song|first1=Xin|last2=Eshra|first2=Abeer|last3=Dwyer|first3=Chris|last4=Reif|first4=John|date=2017-05-25|title=Renewable DNA seesaw logic circuits enabled by photoregulation of toehold-mediated strand displacement|journal=RSC Advances|language=en|volume=7|issue=45|pages=28130–28144|doi=10.1039/C7RA02607B|bibcode=2017RSCAd...728130S|issn=2046-2069|doi-access=free}}</ref><ref>{{Cite journalbook|last1=Goel|first1=Ashish|last2=Ibrahimi|first2=Morteza|chapter=Renewable, Time-Responsive DNA Logic Gates for Scalable Digital Circuits |date=2009|editor-last=Deaton|editor-first=Russell|editor2-last=Suyama|editor2-first=Akira|title=Renewable, Time-Responsive DNA Logic Gates for Scalable Digital Circuits|journal=DNA Computing and Molecular Programming|series=Lecture Notes in Computer Science|volume=5877|language=en|___location=Berlin, Heidelberg|publisher=Springer|pages=67–77|doi=10.1007/978-3-642-10604-0_7|isbn=978-3-642-10604-0}}</ref>

Using strand displacement reactions (SRDs), reversible proposals are presented in [https://www.mdpi.com/2073-8994/13/7/1242 "Synthesis Strategy of Reversible Circuits on DNA Computers" paper] <ref>{{Cite journal|last1=Rofail|first1=Mirna|last2=Younes|first2=Ahmed|date=July 2021|title=Synthesis Strategy of Reversible Circuits on DNA Computers|journal=Symmetry|language=en|volume=13|issue=7|pages=1242|doi=10.3390/sym13071242|bibcode=2021Symm...13.1242R|doi-access=free}}</ref> for implementing reversible gates and circuits on DNA computers by combining DNA computing and reversible computing techniques. This paper also proposes a universal reversible gate library (URGL) for synthesizing n-bit reversible circuits on DNA computers with an average length and cost of the constructed circuits better than the previous methods.

Line 106:

DNA nanotechnology has been applied to the related field of DNA computing. DNA tiles can be designed to contain multiple sticky ends with sequences chosen so that they act as [[Wang tile]]s. A DX array has been demonstrated whose assembly encodes an [[Exclusive or|XOR]] operation; this allows the DNA array to implement a [[cellular automaton]] which generates a [[fractal]] called the [[Sierpinski gasket]]. This shows that computation can be incorporated into the assembly of DNA arrays, increasing its scope beyond simple periodic arrays.<!--

--><ref name="rothemund04winfree">{{Cite journal | last1 = Rothemund | first1 = P. W. K. | last2 = Papadakis | first2 = N. | last3 = Winfree | first3 = E. | doi = 10.1371/journal.pbio.0020424 | title = Algorithmic Self-Assembly of DNA Sierpinski Triangles | journal = PLOS Biology | volume = 2 | issue = 12 | pages = e424 | year = 2004 | pmid = 15583715| pmc =534809 | doi-access = free }}</ref>

== Capabilities ==