Content deleted Content added
No edit summary |
|||
Line 5:
}}
== Overview ==
The origin of Probio DR10™ in the 1990s<ref name=":4" /> marked a notable development in the field of [[Probiotic|probiotics]]. This era saw an increased focus on the role of [[Probiotic|probiotics]] in human health, especially regarding [[gut health]] and [[immune function]]. DR10™, isolated from [[yogurt]]—a common source of probiotics—demonstrates its natural adaptability to the [[human digestive system]]. The strain was initially isolated from yogurt, a traditional and common source of probiotics. The selection of DR10™ from yogurt not only signifies its natural occurrence but also underscores its inherent compatibility with the human gut environment. This origin is fundamental in the context of probiotics, as it suggests a natural symbiosis between the bacteria and the human digestive system.
A significant advancement in the understanding of DR10™ came with the publication of its complete genomic sequence in 2018<ref>{{Cite journal |last=Ibarra |first=Alvin |last2=Latreille-Barbier |first2=Mathilde |last3=Donazzolo |first3=Yves |last4=Pelletier |first4=Xavier |last5=Ouwehand |first5=Arthur C. |date=2018-05-04 |title=Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial |url=https://www.tandfonline.com/doi/full/10.1080/19490976.2017.1412908 |journal=Gut Microbes |language=en |volume=9 |issue=3 |pages=236–251 |doi=10.1080/19490976.2017.1412908 |issn=1949-0976 |pmc=PMC6219592 |pmid=29227175}}</ref>. This detailed genetic information has been essential in ensuring quality control, safety, and purity of the strain, which is critical in the probiotic industry where efficacy and safety are paramount. The adaptability of Probio DR10™ is evidenced by its incorporation into a range of products across the food and beverage, dietary supplement, and pharmaceutical industries<ref name=":3">{{cite journal |last1=Cheng |first1=Jing |last2=Laitila |first2=Arja |last3=Ouwehand |first3=Arthur C. |date=14 December 2021 |title=Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review |journal=Frontiers in Nutrition |volume=8 |doi=10.3389/fnut.2021.790561 |pmc=8712437 |pmid=34970580 |doi-access=free}}</ref>. This reflects the strain's stability and ability<ref name=":3" /><ref name=":0">{{cite journal |last1=Araujo |first1=Lisa Danielly Curcino |last2=Furlaneto |first2=Flávia Aparecida Chaves |last3=da Silva |first3=Léa Assed Bezerra |last4=Kapila |first4=Yvonne L. |date=19 August 2022 |title=Use of the Probiotic Bifidobacterium animalis subsp. lactis HN019 in Oral Diseases |journal=International Journal of Molecular Sciences |volume=23 |issue=16 |pages=9334 |doi=10.3390/ijms23169334 |pmc=9409207 |pmid=36012597 |doi-access=free}}</ref> to retain its beneficial properties in various product forms.
The distinction of Probio DR10™ lies in the scientific research and clinical trials that support its beneficial impact on gut health and immune support<ref>{{Cite journal |last=Cheng |first=Jing |last2=Laitila |first2=Arja |last3=Ouwehand |first3=Arthur C. |date=2021-12-14 |title=Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review |url=https://www.frontiersin.org/articles/10.3389/fnut.2021.790561/full |journal=Frontiers in Nutrition |volume=8 |doi=10.3389/fnut.2021.790561 |issn=2296-861X |pmc=PMC8712437 |pmid=34970580}}</ref>. This research aligns with the growing interest in functional foods and health supplements, and contributes to the broader understanding of specific probiotic strains and their health benefits. Some of the products from Fonterra that contain Probio DR10 are Anmum Essential Gold and Anmum Materna for the Malaysian market.
== Benefits of Probio DR10'''''™''''' ==
Line 17 ⟶ 20:
Probio DR10'''''™''''' demonstrated extensive immune-stimulating effects in animal models as well as healthy adult and elderly clinical studies. In a randomised controlled trial (RCT) conducted with children aged 1 to 3 years, it was found that the incidence of high fever and severe acute lower respiratory infections was reduced by 5% and 35% respectively, in children who received the strain along with a prebiotic, in comparison to those who were administered a placebo.<ref name="Sazawal e12164">{{cite journal |last1=Sazawal |first1=Sunil |last2=Dhingra |first2=Usha |last3=Hiremath |first3=Girish |last4=Sarkar |first4=Archana |last5=Dhingra |first5=Pratibha |last6=Dutta |first6=Arup |last7=Verma |first7=Priti |last8=Menon |first8=Venugopal P. |last9=Black |first9=Robert E. |title=Prebiotic and Probiotic Fortified Milk in Prevention of Morbidities among Children: Community-Based, Randomized, Double-Blind, Controlled Trial |journal=PLOS ONE |date=13 August 2010 |volume=5 |issue=8 |pages=e12164 |doi=10.1371/journal.pone.0012164 |doi-access=free |pmc=2921405 |pmid=20730056 |bibcode=2010PLoSO...512164S }}</ref>
===Modulation of intestinal microbiota===
| |||