Biomolecular Object Network Databank: Difference between revisions

Revision as of 02:31, 25 March 2007

Revision as of 23:43, 4 April 2007

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===Database structure===

BIND contains information on three types of data: interactions, molecular complexes and pathways.

# Interactions are the basic component of BIND and describe how 2 or more objects (A and B) interact with each other. The objects can be a variety of things: [[DNA]], [[RNA]], [[proteinsgenes]], [[ligandsproteins]], [[genesligands]], or [[photons]]. The interaction entry contains the most amount of information about a molecule; it provides information on its name and synonyms, where it is found (e.g. where in the cell, what species, when it is active, etc.), and its sequence or where its sequence can be found. The interaction entry also outlines the experimental conditions required to observe binding in vitro, chemical dynamics (including [[thermodynamics]] and [[kinetics]]).

# The second type of BIND entries are the molecular complexes. Molecular complexes are defined as an aggregate of molecules that are stable a have a function when bound to each other. The record may also contain some information on the role of the complex in various interactions and the molecular complex entry links data from 2 or more interaction records.

# The third component of BIND is the pathway record section. A pathway consists of a network of interactions that are involved in the regulation of cellular processes. This section may also contain information on phenotypes and diseases related to the pathway.