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Un '''microarray di DNA''' (comunemente conosciuto come '''''[[gene]] chip''''', ''chip a DNA'', ''biochip'' o '''matrici ad alta densità''') è un insieme di microscopiche sonde di [[DNA]] attaccate ad una superficie solida come vetro, plastica, o chip di silicio formanti un array (matrice). Tali array permettono di esaminare simultaneamente la presenza di moltissimi geni all'interno di un campione di DNA (che spesso può rappresentare anche tutto il [[genoma]] o il [[trascrittoma]] di un organismo). Un utilizzo tipico è quello di confrontare il profilo di espressione genica di un individuo malato con quello di uno sano per individuare quali geni sono coinvolti nella malattia.
