Diffusing capacity: Difference between revisions

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'''Diffusing capacity''' of the lung (D<sub>L</sub>) (also known as ''transfer factor'') measures the transfer of gas from air in the lung, to the [[red blood cell]]s in lung blood vessels. It is part of a comprehensive series of [[pulmonary function testing|pulmonary function tests]] to determine the overall ability of the [[lung]] to transport gas into and out of the blood. D<sub>L</sub>, especially [[DLCO|D<sub>LCO</sub>]], is reduced in certain diseases of the lung and heart. D<sub>LCO</sub> measurement has been standardized according to a position paper<ref name="multiple">{{cite journal |vauthors=Macintyre N, Crapo RO, Viegi G, etal | year = 2005 | title = Standardisation of the single-breath determination of carbon monoxide uptake in the lung | journal = Eur Respir J | volume = 26 | issue = 4| pages = 720–35 | doi = 10.1183/09031936.05.00034905 | pmid = 16204605 | s2cid = 18177228 | doi-access = free }}</ref> by a task force of the [[European Respiratory Society|European Respiratory]] and [[American Thoracic Society|American Thoracic]] Societies.
 
In [[respiratory physiology]], the diffusing capacity has a long history of great utility, representing [[Electrical resistance and conductance|conductance]] of gas across the alveolar-capillary membrane and also takes into account factors affecting the behaviour of a given gas with hemoglobin.{{Citation needed|reason=uncited definition|date=March 2014}}