Genetic code: Difference between revisions

Content deleted Content added
It is mentioned that the proteolipid code is not yet widely accepted. Interactomes such as the ubiquitin and glycan codes are included in the proteolipid code.
Tag: Reverted
m Reverted edit by Snovel Novelton (talk) to last version by DMacks
Line 2:
{{Use dmy dates|date=August 2016}}
[[File:RNA-codon.svg|thumb|A series of codons in part of a [[messenger RNA]] (mRNA) molecule. Each codon consists of three [[nucleotide]]s, usually corresponding to a single [[amino acid]]. The nucleotides are abbreviated with the letters A, U, G and C. This is mRNA, which uses U ([[uracil]]). DNA uses T ([[thymine]]) instead. This mRNA molecule will instruct a [[ribosome]] to synthesize a protein according to this code.]]
The '''genetic code''' is the set of rules used by living [[cell (biology)|cells]] to [[Translation (biology)|translate]] information encoded within genetic material ([[DNA]] or [[RNA]] sequences of nucleotide triplets, or [[codon]]s) into [[protein]]s. Translation is accomplished by the [[ribosome]], which links [[proteinogenic amino acid]]s in an order specified by [[messenger RNA]] (mRNA), using [[transfer RNA]] (tRNA) molecules to carry amino acids and to read the mRNA three [[nucleotide]]s at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries. The genetic code can be contextualized as the complement of a newly proposed but not yet widely accepted model called the proteolipid code<ref>{{cite journal |last1=Kervin |first1=Troy A. |last2=Overduin |first2=Michael |title=Membranes are functionalized by a proteolipid code |journal=BMC Biology |date=27 February 2024 |volume=22 |issue=1 |pages=46 |doi=https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-024-01849-6}}</ref>.
 
The codons specify which amino acid will be added next during [[protein biosynthesis]]. With some exceptions,<ref name="pmid19131629">{{cite journal | vauthors = Turanov AA, Lobanov AV, Fomenko DE, Morrison HG, Sogin ML, Klobutcher LA, Hatfield DL, Gladyshev VN | title = Genetic code supports targeted insertion of two amino acids by one codon | journal = Science | volume = 323 | issue = 5911 | pages = 259–61 | date = Jan 2009 | pmid = 19131629 | pmc = 3088105 | doi = 10.1126/science.1164748 }}</ref> a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. The vast majority of [[gene]]s are encoded with a single scheme (see the [[Codon tables|RNA codon table]]). That scheme is often referred to as the canonical or standard genetic code, or simply ''the'' genetic code, though [[#Variations|variant codes]] (such as in [[mitochondrion|mitochondria]]) exist.