For non-negative response <math>y</math>, assumption-free GLM framework has been developed.<ref>{{Cite journal |last=Babkin |first=Andrey |title=Assumption-lean regression for non-negative response via variational representation |url=https://www.tandfonline.com/doi/full/10.1080/10618600.2025.2459277 |journal=Journal of Computational and Graphical Statistics |volume=0 |issue=ja |pages=1–13 |doi=10.1080/10618600.2025.2459277 |issn=1061-8600}}</ref> Under this framework, the conditional distribution is no longer limited by exponential families.