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→Expanded genetic codes (synthetic biology): moved bacteria's wikilink up to the first occurence of the paragraph; used abbreviation for E. coli; wikilinked genetic viability. |
→Expanded genetic codes (synthetic biology): "E. coli" -> "E. coli bacteria" to remind the reader that the word has occured previously, had they forgotten the meaning of it. |
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In 2017, researchers in South Korea reported that they had engineered a mouse with an extended genetic code that can produce proteins with unnatural amino acids.<ref>{{cite journal | vauthors = Han S, Yang A, Lee S, Lee HW, Park CB, Park HS | title = Expanding the genetic code of Mus musculus | journal = Nature Communications | volume = 8 | pages = 14568 | date = February 2017 | pmid = 28220771 | doi = 10.1038/ncomms14568 | pmc=5321798| bibcode = 2017NatCo...814568H }}</ref>
In May 2019, researchers reported the creation of a new "Syn61" strain of the ''E. coli'' bacteria. This strain has a fully [[Synthetic biology#Synthetic life|synthetic]] genome that is refactored (all overlaps expanded), recoded (removing the use of three out of 64 codons completely), and further modified to remove the now unnecessary tRNAs and release factors. It is fully [[Genetic viability|viable]] and grows 1.6× slower than its wild-type counterpart "MDS42".<ref name="NYT-20190515">{{cite news |last=Zimmer |first=Carl |author-link=Carl Zimmer |title=Scientists Created Bacteria With a Synthetic Genome. Is This Artificial Life? - In a milestone for synthetic biology, colonies of E. coli thrive with DNA constructed from scratch by humans, not nature. |url=https://www.nytimes.com/2019/05/15/science/synthetic-genome-bacteria.html |archive-url=https://ghostarchive.org/archive/20220102/https://www.nytimes.com/2019/05/15/science/synthetic-genome-bacteria.html |archive-date=2022-01-02 |url-access=limited |url-status=live |date=15 May 2019 |work=[[The New York Times]] |access-date=16 May 2019 }}{{cbignore}}</ref><ref name="NAT-20190515">{{cite journal |author=Fredens, Julius |s2cid=205571025 |display-authors=et al. |title=Total synthesis of Escherichia coli with a recoded genome |date=15 May 2019 |journal=[[Nature (journal)|Nature]] |volume=569 |issue=7757 |pages=514–518 |doi=10.1038/s41586-019-1192-5 |pmid=31092918 |pmc=7039709 |bibcode=2019Natur.569..514F }}</ref>
==Features==
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