Bioinformatics: Difference between revisions

Revision as of 19:58, 15 April 2025

Revision as of 20:08, 15 April 2025

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=== Amino acid sequence ===

The linear [[amino acid]] sequence of a protein is called the [[primary structure]]. The primary structure can be easily determined from the sequence of [[codons]] on the DNA gene that codes for it. In most proteins, the primary structure uniquely determines the 3-dimensional structure of a protein in its native environment. An exception is the [[Prion|misfolded protein[[prion]] protein involved in [[bovine spongiform encephalopathy]]. This structure is linked to the function of the protein. Additional structural information includes the ''[[secondary structure|secondary]]'', ''[[tertiary structure|tertiary]]'' and ''[[quaternary structure|quaternary]]'' structure. A viable general solution to the prediction of the function of a protein remains an open problem. Most efforts have so far been directed towards heuristics that work most of the time.{{citation needed|date=July 2015}}

=== Homology ===