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In conjunction with the thalamus, UB has also been linked to the [[white matter]] of the frontal lobe. Ishihara et al. sought to demonstrate this linkage by observing a patient who was experiencing loss of consciousness. The patient, a 72-year-old male, exhibited utilization behavior after admission into the hospital. An examiner placed objects such as a tissue box, toothpaste and a toothbrush in front of the patient and before any instruction the patient brushed his teeth and picked up the tissue in a manner as if to blow his nose. When asked why he did these actions, he had no reason other than that he wanted to use the objects. Later, the patient was placed in front of a paper and pen and he immediately started to write correct letters and sentences without being told to do so because he felt compelled to write.<ref name=" Ishihara " />
The results showed that a [[lesion]] in the subcortical white matter of the [[superior frontal gyrus]] was the cause of utilization behavior in the patient. A [[coronal section]] of the brain confirmed an infarct, tissue death due to lack of oxygen, in the left [[superior frontal gyrus]] with the main lesion in the subcortical white matter.<ref name="Ishihara"/>
==Diagnosis==
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