Desert Bus for Hope 2024 was the first year to raise enough money to last for 168 hours, a full seven 24-hour days, after viewers rallied to raise the remaining approximately $120,000 needed to reach this goal within an hour and a half, making the milestone within 15 minutes of the deadline. The run ended within $100,000 of the $12 million lifetime milestone; as a result, unless this is surpassed once post-event 2024 donations are tabulated, Desert Bus 2025 is set to be the first single year to pass two lifetime million-dollar milestones.
InAfter having been teased during Desert Bus 2024, in April of 2025, it was announced that Desert Bus would be running a smaller, 'satellite' event in the following month called 'Desert Bus Express', lasting only 24 hours and benefiting BC Cancer Foundation.<ref name=":20">{{cite web |url=https://desertbus.org/express2025/?id=67fd733c6552c100016c967f |title=Announcing Desert Bus Express! |website=Desert Bus for Hope |access-date= 24 May 2025}}</ref> The event would be remote, using the systems developed for Desert Bus 2020.<ref name=":21">{{cite web |url=https://desertbus.org/express2025/info/about |title=About Desert Bus Express |website=Desert Bus for Hope |access-date= 24 May 2025}}</ref>
