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===Codon usage bias===
{{Main|Codon usage bias}}
The frequency of codons, also known as [[codon usage bias]], can vary from species to species with functional implications for the control of [[translation (biology)|translation]]. The codon varies by organism; for example, most common proline codon in E. coli is CCG, whereas in humans this is the least used proline codon.<ref>{{Cite web|title=Codon Usage Frequency Table(chart)-Genscript|url=https://www.genscript.com/tools/codon-frequency-table|access-date=2022-02-04|website=www.genscript.com}}</ref>
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