Biomaterial surface modifications: Difference between revisions

Revision as of 07:39, 28 May 2025

Latest revision as of 05:14, 19 July 2025

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=== Guide Wires ===

Guide wires are an example of an application for biomedical coatings. Guide wires are used in [[percutaneous coronary intervention|coronary angioplasty]] to correct the effects of [[coronary artery disease]], a disease that allows plaque build up on the walls of the arteries. The guide wire is threaded up through the femoral artery to the obstruction. The guide wire guides the balloon catheter to the obstruction where the catheter is inflated to press the plaque against the arterial walls.<ref name=angioplasty>{{cite web |url=https://www.nlm.nihmedlineplus.gov/medlineplus/ency/anatomyvideos/000096.htm |title= Percutaneous transluminal coronary angioplasty (PTCA) |last1= Gandelman |first1= Glenn |date= March 22, 2013 |work= Medline Plus |accessdateaccess-date=19 May 2013}}</ref> Guide wires are commonly made from stainless steel or [[Nickel Titanium|Nitinol]] and require polymer coatings as a surface modification to reduce friction in the arteries. The coating of the guide wire can affect the trackability, or the ability of the wire to move through the artery without kinking, the tactile feel, or the ability of the doctor to feel the guide wire's movements, and the thrombogenicity of the wire.

==== Hydrophilic Coatings ====