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<li>There are very few true contraindication and precaution conditions. Only two of these conditions are generally considered to be permanent: severe (anaphylactic) allergic reaction to a vaccine component or following a prior dose of a vaccine, and encephalopathy not due to another identifiable cause occurring within 7 days of pertussis vaccination<ref> {{cite web|url=http://www.cdc.gov/nip/publications/pink/genrec.pdf |title=General Recommendations on Immunizations |accessdate=2007-05-12 |date=2007-02-14 |format=PDF |work=Epidemiology & Prevention of Vaccine-Preventable Diseases--The Pink Book 10th Edition |publisher=Centers for Disease Control and Prevention }}</ref>.</li>
<li>Only the diluent supplied by the manufacturer should be used to reconstitute a freeze-dried vaccine. A sterile needle and sterile syringe must be used for each vial for adding the diluent to the powder in a single vial or ampoule of freeze-dried vaccine<ref>{{cite news | first= | last=Department of Vaccines and Biologicals | coauthors= | title=WHO Recommendations for Diluents | date=2000-12 | publisher=World Health Organization | url =http://www.who.int/vaccines-documents/DoxNews/updates/updat34e.pdf | work =Vaccines and Biologicals Update | pages =3 | accessdate = 2007-05-12 | language = }}</ref>.</li>
<li>The only way to be completely safe from exposure to blood-borne diseases from injections, particularly hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) is to use one sterile needle, one sterile syringe for each child<ref>{{cite news | first=Edward | last=Hoekstra | coauthors= | title=Immunization: Injection Safety | date= | publisher=UNICEF | url =http://www.unicef.org/immunization/23244_safety.html | work =UNICEF Expert Opinion | pages = | accessdate = 2007-05-12 | language = }}</ref>.
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