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[[File:Innate immune system.png|thumb|Innate immune system]]
The '''innate immune system''' or '''nonspecific immune system'''<ref>{{Cite web|title=Immune response: MedlinePlus Medical Encyclopedia|url=https://medlineplus.gov/ency/article/000821.htm|access-date=2021-11-07|website=medlineplus.gov|language=en}}</ref> is one of the two main immune systemimmunity subclassesstrategies in [[vertebrate]]s. ;(the other being the [[adaptive immune system]]). subclassThe innate immune system is [[adaptivean alternate defense strategy and is the dominant immune system response found in [[plant]]s, [[fungi]], [[prokaryote]]s, and [[invertebrate]]s (see {{Section link||Beyond vertebrates}}).<ref name="Janeway">{{cite book | vauthors = Janeway C, Paul C, Travers M, Walport M, Shlomchik M | author-link = Charles Janeway | title = Immunobiology | edition = Fifth | publisher = Garland Science | year = 2001 | ___location = New York and London| url = https://www.ncbi.nlm.nih.gov/books/NBK10757/?depth=10| isbn = 0-8153-4101-6}}.</ref>
The major functions of the innate immune system are to: ▼An innate immune system is a functional system of immunity(recovery process) which is innate(not being modified after born). It is typical immune system of [[plant]]s, [[fungi]], [[prokaryote]]s, and [[invertebrate]]s (see {{Section link||Beyond vertebrates}}).<ref name="Janeway">{{cite book | vauthors = Janeway C, Paul C, Travers M, Walport M, Shlomchik M | author-link = Charles Janeway | title = Immunobiology | edition = Fifth | publisher = Garland Science | year = 2001 | ___location = New York and London| url = https://www.ncbi.nlm.nih.gov/books/NBK10757/?depth=10| isbn = 0-8153-4101-6}}.</ref>
* recruitingrecruit immune cells to invasioninfection sites by producing chemical factors , (Eg.including chemical mediators called [[cytokine]]s )▼
* activatingactivate the [[complement cascade]] to identify [[bacteria]], activatingactivate cells, and promotingpromote clearance of [[immune complex|antibody complexes]] or dead cells ▼▲The major functions of the innate immune system:
* identifyingidentify and removingremove foreign substances present in bodyorgans, tissues, blood and [[lymph]], by specialized [[white blood cell]]s ▼▲* recruiting immune cells to invasion sites by producing chemical factors (Eg. chemical mediators called [[cytokine]]s)
* activatingactivate the [[adaptive immune system]] through [[antigen presentation]] ▼▲* activating the [[complement cascade]] to identify [[bacteria]], activating cells, and promoting clearance of [[immune complex|antibody complexes]] or dead cells
* act as a physical and chemical barrier to infectious agents; via physical measures such as skin and mucus, and chemical measures such as [[clotting factor]]s and [[host defence peptide]]s.
▲* identifying and removing foreign substances present in body by specialized [[white blood cell]]s
▲* activating the [[adaptive immune system]] through [[antigen presentation]]
* forming physical barriers (eg. skin) and chemical matters (mucus, [[Coagulation|clotting factors]], and host defense peptides) against infectious agent (i.e. [[pathogen]]).
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* [[NOD-like receptor]]
* [[Endothelial cell tropism]]
* [[Selnoflast]]
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