Diffusing capacity: Difference between revisions

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J<sup>*</sup><sub>O2</sub> is the uptake of oxygen (ml/min). P<sub>AO2</sub> is the alveolar partial pressure of oxygen. P<sub>cO2</sub> is the [[partial pressure]] of oxygen in the alveolar capillary. Thus, the higher the diffusing capacity DL, the more gas will be transferred across the alveolar-capillary membrane for a given gradient in partial pressure (or concentration) of the gas.
 
Because it is difficult to measure the capillary partial pressure of oxygen, [[carbon monoxide]] (CO) is used as the test gas to measure the diffusing capacity (Dlco), in europeEurope this is called transfer factor (TLco). Because CO is so tightly bound to hemoglobin in the red blood cells, the partial pressure of CO in the capillaries is assumed to be zero. Thus,
 
:<math>D_LCO = \frac {J^*_{CO}}{P_{ACO}}</math>