Entire arrays have obvious flaws detectable by visual inspection, pairwise comparisons to arrays in the same experimental group, or by analysis of RNA degredationdegradation<ref>{{cite journal |author=Wilson CL, Miller CJ |title=Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis |journal=Bioinformatics |volume=21 |issue=18 |pages=3683–5 |year=2005 |pmid=16076888 |doi=10.1093/bioinformatics/bti605}}</ref>. Results may improve by removing these arrays from the analysis entirely.
