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This resource depicts information on human protein functions including [[protein-protein interactions]], [[post-translational modifications]], enzyme-substrate relationships and [[disease]] associations. Protein annotation information that is catalogued was derived through manual curation using published literature by expert biologists and through bioinformatics analyses of the protein sequence. HPRD also integrates data from [[Human Proteinpedia]], a community portal for integrating human protein data. The data from HPRD can be freely obtained and commercial entities may not use this site without prior licensing authorization. Human Proteinpedia<ref>Mathivanan et al. Human Proteinpedia enables sharing of human protein data. Nat Biotechnology. 2008 Feb;26:164-7</ref> content is freely available for anyone to download and use.
HPRD data is available for download in tab delimited and [[XML]] file formats.
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