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In [[organic chemistry]], the '''saline-sodium citrate (SSC) buffer''' is a hybridisation [[buffer (chemistry)|buffer]]. It is used in [[molecular biology]] for washing and to control stringency, for example in [[Southern blotting]] or [[Northern blotting]].
The 20× stock solution consists of 3 [[molar (concentration)|M]] [[sodium chloride]] and 300 [[milli-|m]]M [[trisodium citrate]] (adjusted to [[pH]] 7.0 with [[hydrochloric acid|HCl]]).
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