Sequence clustering: Difference between revisions

Revision as of 19:26, 28 May 2005

Revision as of 09:36, 17 November 2005

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In [[bioinformatics]], '''[[Primary structure|sequence]] clustering''' [[algorithm]]s attempt to group sequences that are somehow related. The sequences can be either of genomic, "transcriptomic" ([[expressed sequence tag|ESTs]]) or [[protein]] origin.

sequences that are somehow related. The sequences can be either of genomic, "transcriptomic" ([[expressed sequence tag|ESTs]]) or [[protein]] origin.

For proteins, [[Homology (biology)|homologous]] sequences are typically grouped into [[protein family|families]]. For EST data, clustering is important to group sequences originating from the same [[gene]] before the ESTs are [[sequence assembly|assembled]] to reconstruct the original [[mRNA]].

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Sequence clusters are often synonymous with (but not identical to) [[protein family|protein families]]. Determining a representative [[tertarytertiary structure|structure]] for each ''sequence cluster''' is the aim of many [[structural genomics]] initativesinitiatives.

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