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The '''cardiac neural crest''' is a form of [[neural crest]].<ref name="urlThe Neural Crest">{{cite web |url=http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=dbio.section.3109 |title=The Neural Crest |format= |work= |accessdate=2009-05-31}}</ref>
The '''cardiac neural crest''' develops from the dorsal neural tube.<ref name="pmid18292601">{{cite journal |author=Sun X, Zhang R, Lin X, Xu X |title=Wnt3a regulates the development of cardiac neural crest cells by modulating expression of cysteine-rich intestinal protein 2 in rhombomere 6 |journal=Circ. Res. |volume=102 |issue=7 |pages=831–9 |year=2008 |month=April |pmid=18292601 |doi=10.1161/CIRCRESAHA.107.166488 |url=http://circres.ahajournals.org/cgi/pmidlookup?view=long&pmid=18292601}}</ref> It overlaps the vagal neural crest and migrates to populate the [[branchial arches|pharyngeal arches]] 3, 4 and 6 (producing structures in the head) and to the [[heart]], forming connective tissue that separates the great vessels of the heart.
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