X-linked dominant inheritance: Difference between revisions

Revision as of 08:08, 5 September 2009

Revision as of 08:20, 5 September 2009

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'''X-linked dominant''' inheritance, sometimes referred to as '''X-linked dominance''', is a mode of [[genetics|genetic inheritance]] by which a [[dominant gene]] is carried on the [[X chromosome]]. As a diseasean inheritance pattern, it is less common than [[X-linked recessive]]. In medicine, X-linked dominant inheritance indicates that a gene responsible for a [[genetic disorder]] is located on the X chromosome, and only one copy of the gene is sufficient to cause the disorder when inherited from a parent who has the disorder.

== Inheritance ==

In medicine, X-linked dominant inheritance indicates that a gene responsible for a [[genetic disorder]] is located on the X chromosome, and only one copy of the gene is sufficient to cause the disorder when inherited from a parent who has the disorder.

As the X chromosome is one of the [[sex chromosome]]s (the other being the [[Y chromosome]]), X-linked

inheritance is determined by the [[gender]] of the parent carrying a specific gene and can often seem complex. This is due to the fact that, typically, [[female]]s have two copies of the X-chromosome, while [[male]]s have only one copy. The difference between [[Dominance (genetics)#Dominant trait|dominant]] and [[Dominance (genetics)#Recessive|recessive]] inheritance patterns also plays a role in determining the chances of a child inheriting an X-linked disorder from their parentage.

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{| class=wikitable border=1 cellpadding=5 cellspacing=0 align=right width=400

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| align=rightcenter valign=bottom|[[Image:Xlink dominant mother.jpg|thumb|175px]] || align=left valign=bottom|[[Image:X-link dominant father.jpg|thumb|175px]]

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| align=center colspan=2 valign=top|<small>X-linked dominant inheritance works differently depending upon whether the mother (left image) or father (right image) is the carrier of a gene that causes a disease or disorder.</small>