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GHB was first synthesized in the early 1960s by Dr. H. Laborit to use in studying the neurotransmitter [[GABA]]. It quickly found a wide range of uses due to its minimal side effects and controlled action, the only difficulty being the narrow safe dosage range. It should not be taken with alcohol.
Excessive doses can lead to unconsciousness. The Australian practice of putting [[ice]] cubes into the [[rectum]] of GHB users who have fallen unconscious has no medical benefits. <!-- Yes, really. See external link, below --->
Its use recreationally and as a [[date rape]] drug in the 1990s led to it being placed in the [[US]] on Schedule I of the Controlled Substances Act in March 2000. In the [[UK]] it was made a class C drug in June 2003.
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GBL, or [[gamma-butyrolactone]], a chemical precursor of GHB, has effects very similar to GHB but is argued to be more toxic.
== External link ==
* [http://www.heraldsun.news.com.au/common/story_page/0,5478,7361585%5E1702,00.html Warning on ice cube enemas]
[[de: GHB]]
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