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Scientific studies have examined the relationship between coffee consumption and an array of medical conditions. Findings are contradictory as to whether coffee has any specific health benefits, and results are similarly conflicting regarding negative effects of coffee consumption.<ref name=Kummer2003>Kummer, Corby (2003). ''[http://books.google.com/books?id=qNLrJqgfg7wC The Joy of Coffee]'', [http://books.google.com/books?id=qNLrJqgfg7wC&pg=PA151&sig=zL7_XqPYPeBVq8vs3ukYFuwjn2I Caffeine and Decaf], Houghton Mifflin Cookbooks, 160-165. ISBN:0618302409 Retrieved on [[February 23]], [[2008]].</ref>
 
Coffee appears to reduce the risk of [[Alzheimer's disease]], [[Parkinson's disease]], [[heart disease]], [[diabetes mellitus type 2]], [[cirrhosis]] of the [[liver]],<ref>Klatsky, Arthur L.; Morton, C.; Udaltsova, N.; Friedman, D. (2006). "[http://archinte.ama-assn.org/cgi/content/full/166/11/1190 Coffee, Cirrhosis, and Transaminase Enzymes]". ''Archives of Internal Medicine'' 166(11):1190–1195. DOI:10.1001/archinte.166.11.1190 PMID:16772246
Retrieved on [[February 23]], [[2008]].</ref> and [[gout]]. Some health effects are due to the [[caffeine]] content of coffee, as the benefits are only observed in those who drink caffeinated coffee, while others appear to be due to other components.<ref>Pereira, Mark A.; Parker, D.; Folsom, A.R. (2006). "[http://archinte.ama-assn.org/cgi/content/full/166/12/1311 Coffee consumption and risk of type 2 diabetes mellitus: an 11-year prospective study of 28 812 postmenopausal women]". ''Archives of Internal Medicine'' 166(12):1311–1316. PMID:16801515 Retrieved on [[February 23]], [[2008]].
</ref> For example, the [[antioxidant]]s in coffee prevent [[Radical (chemistry)|free radicals]] from causing cell damage.<ref>Bakalar , Nicholas (2006-08-15). [http://www.nytimes.com/2006/08/15/health/nutrition/15coff.html?ex=1313294400&en=d420f19ee1c77365&ei=5088&partner=rssnyt&emc=rss Coffee as a Health Drink? Studies Find Some Benefits]. New York Times. Retrieved on [[July 28]], [[2007]].</ref>
 
Coffee's negative health effects are mostly due to its [[caffeine]] content. Research suggests that drinking caffeinated coffee can cause a temporary increase in the stiffening of arterial walls.<ref>Mahmud, A.; Feely, J. (2001). "[http://hyper.ahajournals.org/cgi/content/full/38/2/227 Acute Effect of Caffeine on Arterial Stiffness and Aortic Pressure Waveform]". ''Hypertension'' 38(2):227–231. PMID:11509481 Retrieved on [[February 23]], [[2008]].
</ref> Excess coffee consumption may lead to a [[magnesium deficiency (medicine)|magnesium deficiency]] or [[hypomagnesaemia]],<ref>Johnson, S. (2001). "[http://www.george-eby-research.com/html/wide-mag-deficiency-path.pdf The multifaceted and widespread pathology of magnesium deficiency]". ''Medical Hypotheses'' 56(2):163-170. Harcourt Publishers Ltd. DOI:10.1054/mehy.2000.1133 PMID:11425281 Retrieved on [[February 23]], [[2008]].</ref> and may be a risk factor for [[Coronary_heart_disease|coronary heart disease]]. Some studies suggest that it may have a mixed effect on [[short-term memory]], by improving it when the information to be recalled is related to the current [[train of thought]], but making it more difficult to recall unrelated information.<ref>BBC News; Lesk, Valerie (2004-07-20). [http://news.bbc.co.uk/2/hi/health/3909085.stm A coffee can make you forgetful]. BBC News. Retrieved on [[February 23]], [[2008]].</ref> About 10% of people with a moderate daily intake (235 mg per day) reported increased depression and anxiety when caffeine was withdrawn,<ref>Smith, A. (2002). "[http://www.erowid.org//references/refs_view.php?A=ShowDocPartFrame&ID=6685&DocPartID=6196 Effects of caffeine on human behavior]". ''Food and Chemical Toxicology'' 40(9):1243-1255. DOI:10.1016/S0278-6915(02)00096-0 PMID:12204388 Retrieved on [[February 23]], [[2008]].</ref> and about 15% of the general population report having stopped caffeine use completely, citing concern about health and unpleasant side effects.<ref>Johns Hopkins University School of Medicine (2003). [http://www.caffeinedependence.org/caffeine_dependence.html#sources Use and Common Sources of Caffeine].
''Information about Caffeine Dependence''. Retrieved on [[February 23]], [[2008]].</ref> Nevertheless, the mainstream view of medical experts is that drinking three 8-ounce (236 ml) cups of coffee per day (considered average or moderate consumption) does not have significant health risks for adults.<ref>Haines, Cynthia Dennison (2007). [http://www.nlm.nih.gov/medlineplus/ency/article/002445.htm Caffeine in the diet]. ''MedlinePlus Medical Encyclopedia''. The U.S. National Library of Medicine. Retrieved on [[February 23]], [[2008]].</ref>
 
== References ==