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==Zurich==
In [[1941]], he accepted the invitation of [[Lavoslav Ruzicka|Lavoslav Ružička]] and left for [[Zurich]], to the [[ETH Zurich|Swiss Federal Institute of Technology]] (''ETH'' - [[Eidgenössische Technische Hochschule]]). He was promoted, starting as private senior lecturer and ending up becoming [[professor]]. After Ružička's retirement in [[1957]], Prelog took over the organic chemistry laboratory where he expanded its activity to unusual areas: [[heterocyclic compounds]], alkaloids, [[alicyclic compounds]], and the isolation and study of biochemically active compounds found in smaller quantities in animal organisms. He also studied the structure of [[antibiotics]] and the [[stereochemistry]] of [[enzyme]] reactions.
His research has contributed to the explanation of the structure of [[steroids]], [[triterpene]], quinine, [[strichnine]], [[solanine]] and other alkaloids introducing so-called Prelog's regulation, which defines the [[conformation]]al relations between reactants and products. Working with [[Robert Cahn]] and [[Christopher Ingold]], he formulated the so-called [[CIP system]], applied generally in [[stereometry]]. Thanks to him and Ružička, both Nobel prize winners of [[Croatia]], Zurich has become one of the most significant centers of modern [[organic chemistry]].
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