Multiple sequence alignment: Difference between revisions

Revision as of 06:58, 14 February 2006

Revision as of 06:58, 14 February 2006

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{{Category:Computational Phylogenetics}}

In [[Bioinformatics]], multiple alignment can be used to study [[evolutionary]] relationships between related [[proteins]]. Since the changes between gene sequences due to evolution are incremental, we can take homologous genes , i.e. genes with a common evolutionary origin, from a diverse range of organisms and then compare them by aligning identical or similar [[residues]]. The comparison of these related genes may then be used to study, which regions of genes have been conserved, and which are sensitive to [[mutation]], over the years. This is very useful in designing experiments to test and modify the function of specific proteins, and to predict the function and [[protein structure|structure of proteins]], and to identify new members of protein families.

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==External links==

[http://www.ebi.ac.uk/clustalw/ ClustalW]

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{{Category:Computational Phylogenetics}}