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[[Germany | German]] [[physician]] [[Karl Wernicke]] followed up on the work done by Broca by studying language deficits unlike those shown by Broca's aphasics. Wernicke noticed that not all deficits were in speech production, but rather linguistic. He found that damage to the left [[Anatomical terms of ___location | posterior]], superior [[temporal lobe | temporal]] [[gyrus]] resulted in deficits in language comprehension rather than speech production. This region is now referred to as [[Wernicke's area]], and the associated syndrome is known as [[Wernicke's aphasia]], for his discovery.
====Advance in
All these seminal works on hemispheric specialization were done on patients and/or postmortem brains, raising questions about the potential impact of pathology on the research findings. New methods permit the ''[[in vivo]]'' comparision of the hemispheres in healthy subjects. Particularly, [[magnetic resonance imaging]] (MRI) and [[positron emission tomography]] (PET) are of importance because of their high spatial resolution and ability to image subcortical brain structures.
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