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==The sign problem in physics==
In physics, the sign problem is typically (but not exclusively) encountered in calculations of the properties of a quantum mechanical system with large number of strongly-interacting [[fermion|fermions]], or in field theories involving a non-zero density of strongly-interacting fermions. Because the particles are strongly interacting, [[perturbation theory]] is inapplicable, and one is forced to use brute-force numerical methods. Because the particles are fermions, their [[wavefunction]] changes sign when any two fermions are interchanged (due to the symmetry of the wave function, see [[Pauli principle]])
The sign problem is one of the major unsolved problems in the physics of many-particle systems, impeding progress in many areas:
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