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:I had a go at putting something of that sort in the intro, but found it worked better to modify the small-molecule paragraph that starts the history section. [[User:Dcrjsr|Dcrjsr]] ([[User talk:Dcrjsr|talk]]) 23:02, 6 April 2012 (UTC)
::The point here are not small molecules, but telling something like this: ''Validation of experimental structures of biological macromolecules is important because they are determined with a relatively low precision (around +-0.3 A for for a good resolution crystal structure and +-1.5 A for solution NMR models ?)''. Let's also check if I understood this correctly: "The validation has three aspects: 1) checking on the validity of the thousands to millions of measurements in the experiment..." Are we talking about evaluating quality of data prior to generating models? For example, one can not expect a good quality all-atom structure from 6A resolution EM data, orientational constraints by solid state NMR or IR data. [[User:My very best wishes|My very best wishes]] ([[User talk:My very best wishes|talk]]) 14:08, 7 April 2012 (UTC)
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