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In [[biochemistry]] and [[molecular biology]], the '''saline-sodium citrate (SSC) buffer''' is used as a hybridization [[buffer (chemistry)|buffer]], to control stringency for washing steps in protocols for [[Southern blotting]], [[in situ hybridization]], [[DNA Microarray]] or [[Northern blotting]]. 20X SSC may be used to prevent drying of [[agarose gel]]s during a vacuum transfer.
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