Role of cell adhesions in neural development: Difference between revisions

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|title=Summary of CRASH conditions
|hdrs=Year!!Comments
|row1=Corpus callosum [[hypoplasia]] {{!!}} Incomplete corpus-callosum development
|row2=Retardation {{!!}} Impaired cognitive function
|row3=Adducted thumbs {{!!}} Abnormal thumb development
|row4=Spastic [[paraplegia]] {{!!}} Stiffening and contraction in the lower limbs
|row5=[[Hydrocephalus]] {{!!}} Abnormal accumulations of [[Cerebrospinal fluid]] within skull}}
 
*Additionally, studies have shown that alterations in the expression of the protein thy-1 may be partially responsible for the abnormal neuronal outgrowth observed in Alzheimer's patients. It was found that abnormal neural outgrowth and thy-1 presence were correlated spatially, though mechanistic work is still needed to better understand thy-1's involvement in this condition.<ref>{{cite journal|last=Leifer|first=D|title=Thy-1 in hippocampus: normal anatomy and neuritic growth in Alzheimer's disease.|journal=Journal of Neuropathology & Experimental Neurology|year=1992|month=March|volume=51|issue=2|pages=133-41}}</ref>