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A common approach for multiple sequence alignment is to progressively align sequences using a guide tree. Initially, each sequence at the leaves is represented as a trivial alignment of a single sequence. Then, at each internal node, the alignments at its children are merged into an alignment of the alignments. At the end, the root contains an alignment on all the sequences. This is called ''progressive alignment''.
There are many computer programs to produce multiple sequence alignments starting with a collection of unaligned sequences ([[Clustal|ClustalW]], [[DIALIGN]], [[MAVID]], [[TBA]], [[T-Coffee]]) and to represent graphically those alignments ([[Clustal|ClustalW]], [http://www.sanger.ac.uk/Software/Pfam/help/belvu_setup.shtml Belvu]).
== References ==
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