ItThe was'''Kokko previouslyand thoughtRector thatmodel''' is a theory explaining the mechanism of generation of a gradient wasin generatedthe by[[inner medulla]] of the [[kidney]]. Unlike earlier theories explaining the mechanism using counter current mechanism (as is the case in the [[outer medulla]])., Butthe itdriving force for salt reabsorption is stated to be urea accumulation. It has been provenproved that thiscounter current mechanism cannot be the case in the [[inner medulla]], since there are no salt pumps, and the [[cell membrane]] is too [[Semipermeable membrane|permeable]] to salt.▼
The '''Kokko and Rector model''' is a theory to explain how a gradient is generated in the [[inner medulla]] of the [[kidney]].
▲It was previously thought that the gradient was generated by the counter current mechanism (as is the case in the [[outer medulla]]). But it has been proven that this cannot be the case in the [[inner medulla]], since there are no salt pumps, and the [[cell membrane]] is too [[Semipermeable membrane|permeable]] to salt.
The Kokko and Rector model suggests that in the inner medulla the driving force for salt reabsorption is urea accumulation.
