Multi-Omics Profiling Expression Database: Difference between revisions

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The '''Multi-Omics Profiling Expression Database''' ('''MOPED''') is an expanding proteomicsmulit-omics resource that supports rapid browsing of proteintranscriptomics expressionand proteomics information from publicly available studies on model organisms and humans. MOPED is designed to simplify the comparison and sharing of proteomics data for the greater research community. MOPED employs the standardized analysis pipeline [https://www.proteinspire.org/ SPIRE] to uniquely provide protein level expression data, meta- analysis capabilities and quantitative data. Data can be queried for specific proteins and gene, browsed based on organism, tissue, localization and condition and sorted by false discovery rate and expression. MOPED empowers users to visualize their own expression data and compare it with existing studies. Further, MOPED links to various protein and pathway data- bases, including [[GeneCards]], [http://www.pantherdb.org/ Panther], [[Entrez]], [[UniProt]], [[KEGG]], [http://www.theseed.org/wiki/Home_of_the_SEED SEED], and [[Reactome]]. Protein identifiers are integrated from GeneCards (cross-referenced with MOPED), [[Genbank|GI]], [[RefSeq]], [http://www.ebi.ac.uk/ena/about/locus_tag Locus Tag], [[UniProt]], [[WormBase]], and [[Saccharomyces Genome Database|SGD]]. The current version of MOPED (MOPED 2.05, 20122014) contains over 43000 proteins with at least one spectral match and more than 11 million high certainty spectra. MOPED is developed and supported by the [http://kolkerlab.proteinspire.org/ Kolker] team at [http://www.seattlechildrens.org/research/ Seattle Children's Research Institute].

MOPED was previously known as the Model Organism Protein Expression Database, before changing its name to the Multi-Omics Profiling Expression Database.

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== Further reading ==

{{refbegin}}

* {{cite journal | author = Higdon R, Stewart E, Stanberry L, Haynes W, Choiniere J, Montague E, Anderson N, Yandl Y, Janko I, Broomall W, Fishilevich S, Lancet D, Kolker N, Eugene Kolker. | title = MOPED enables discoveries through consistently processed proteomics data. | journal = J Proteome Res | volume = 13 | issue = 1 | pages = 107-113 |date=Jan 2014 | pmid = 24350770 | doi = 10.1021/pr400884c }}

* {{cite journal | author = Kolker E, Higdon R, Morgan P, Sedensky M, Welch D, Bauman A, Stewart E, Haynes W, Broomall W, Kolker N | title = SPIRE: Systematic protein investigative research environment | journal = J Proteomics | volume = 75 | issue = 1 | pages = 122–6 |date=December 2011 | pmid = 21609792 | doi = 10.1016/j.jprot.2011.05.009 }}

* {{cite journal | author = Stelzer G, Dalah I, Stein TI, Satanower Y, Rosen N, Nativ N, Oz-Levi D, Olender T, Belinky F, Bahir I, Krug H, Perco P, Mayer B, Kolker E, Safran M, Lancet D | title = In-silico human genomics with GeneCards | journal = Hum. Genomics | volume = 5 | issue = 6 | pages = 709–17 |date=October 2011 | pmid = 22155609 | pmc = 3525253 | doi = | url = }}