Cardiac neural crest: Difference between revisions

Content deleted Content added
Disambiguated: signalingRecognition signal
m Molecular pathways: Replace unicode entity nbsp for character [NBSP] (or space) per WP:NBSP + other fixes, replaced: → using AWB (10331)
Line 30:
 
== Molecular pathways ==
Many signaling molecules are required for the differentiation, proliferation, migration and [[apoptosis]] of the CNCCs. The molecular pathways involved include the [[Wnt signaling pathway|Wnt]], [[Notch signaling  pathway|Notch]], [[Bone Morphogenetic Protein|BMP]], [[FGF8]] and [[GATA transcription factor|GATA]] families of molecules. In addition to these signaling pathways, these processes are also mediated by environmental factors including blood flow, shear stress, and blood pressure.<ref name="Niessen (2008)"/>
 
The CNCCs interact with the cardiogenic mesoderm cells of the primary and secondary heart fields, which are derived from the cardiac crescent and will give rise to the [[endocardium]], myocardium, and [[epicardium]]. The CNCCs themselves are the precursors to vascular smooth muscle cells and cardiac neurons.<ref name="Brown (2006)">Brown C. and Baldwin H. "Neural crest contribution to the cardiovascular system." Advances in Experimental Medicine 2006, 589 p134 - 154 doi 10.1007/978-0-387-46954-6_8. Accessed 19 November 2012.</ref>