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== Molecular pathways ==
Many signaling molecules are required for the differentiation, proliferation, migration and [[apoptosis]] of the CNCCs. The molecular pathways involved include the [[Wnt signaling pathway|Wnt]], [[Notch signaling
The CNCCs interact with the cardiogenic mesoderm cells of the primary and secondary heart fields, which are derived from the cardiac crescent and will give rise to the [[endocardium]], myocardium, and [[epicardium]]. The CNCCs themselves are the precursors to vascular smooth muscle cells and cardiac neurons.<ref name="Brown (2006)">Brown C. and Baldwin H. "Neural crest contribution to the cardiovascular system." Advances in Experimental Medicine 2006, 589 p134 - 154 doi 10.1007/978-0-387-46954-6_8. Accessed 19 November 2012.</ref>
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