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Line 5: ==Examples of Upstream Activation Sequences in Research== ===''GAL1-GAL10'' Intergenic Region=== Several studies have been conducted with ''Saccharomyces cerevisiae'' to explore the exact function of upstream activation sequences, often focusing on the GAL1-GAL10 intergenic region [https://www.wikigenes.org/e/gene/e/852307.html]. Its property to bind the GAL4 protein is utilised in the [[GAL4/UAS system\|GAL4/UAS technique]] for controlled gene misexpression in Drosophila. In this technique, four related binding sites between the GAL10 and GAL1 loci in ''Saccharomyces cerevisiae'' serve as an Upstream Activating Sequences (UAS) element through GAL4 binding.<ref>{{cite journal\|last1=Duffy\|first1=Joseph B.\|title=GAL4 system in Drosophilia: A Fly Geneticist's Swiss Army Knife\|journal=Genesis\|date=2002\|volume=34\|issue=1-2\|pages=1-15}}</ref>.

Upstream activating sequence: Difference between revisions