Upstream activating sequence: Difference between revisions

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An '''upstream activation sequence''' (UAS) is a [[Cis-regulatory element|cis-acting regulatory sequence]]. It is distinct from the [[promotor (biology)|promoter]] and increases the [[Transcription (genetics)|expression]] of a neighbouring [[gene]]. Due to its essential role in activating transcription, the upstream activating sequence is often considered to be analogous to the function of the enhancer[[Enhancer (genetics)]] in multicellular eukaryotes.<ref>{{cite journal|last1=Webster|first1=Nocholas|last2=Jin|first2=Jia Rui|last3=Green|first3=Stephen|last4=Hollis|first4=Melvyn|last5=Chambon|first5=Pierre|title=The Yeast UAS{{sub|G}} is a transciptional enhancer in human hela cells in the presence of the GAL4 trans-activator|journal=Cell|date=29 January 1988|volume=52|issue=2|pages=169-178}}</ref>

==Examples of Upstream Activation Sequences in Research==