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A '''Guideline Execution Engine''' is a [[computer program]] which can interpret a [[guideline (medical)|clinical guideline]] represented in a computerized format and perform actions towards the user of an [[electronic medical record]].
A Guideline Execution Engine needs to communicate with a host [[Clinical information system]]. [[virtual Medical Record|vMR]] is one possible interface which can be used.
The engine's main function is to manage instances of executed guidelines of individual patients.
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