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==Content==
CDD content includes NCBI manually curated ___domain models and ___domain models imported from a number of external source databases ([[Pfam]], SMART, COG, PRK, [[TIGRFAMs]]). What is unique about NCBI-curated domains is that they use 3D-structure information to explicitly define ___domain boundaries, align blocks, amend alignment details, and provide insights into sequence/structure/function relationships. Manually curated models are organized hierarchically if they describe ___domain families that are clearly related by common descent. To provide a non-redundant view of the data, CDD clusters similar ___domain models from various sources into superfamilies. hhh
==Searching the database==
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